Thursday, November 21, 2013

The Intraclass Correlation Coefficient (ICC) and the Z Fisher Transformation for the 95% Confidence Interval


Case Scenario
Suppose that there are 10 subjects with eyelid measurements from three different observes (making the total sample = 30), who used a new computerized technique to get eyelid images and later measured the parameters using image J software. What would you do to test for reliability of measurements and how would you go by performing this analysis? Please note that the dependent variable (eyelid measurement) is a continuous variable. This is a real example.

Approach
The best measure of reliability for continuous data is the Intraclass Correlation Coefficient (ICC). The ICC would inform you about the inter-rater reliability, where the higher the ICC the less unique information each additional measure provides.